Synthesis and characterization of a new complex based on antibiotic: Zirconium complex

Abstract It is well known that sulfonamide derivatives, through exchange of different functional groups without modification the –S(O) 2 N(H)– function, can exhibit a wide variety pharmacological activities. In addition, some metal complexes these ligands have been prepared to promote rapid healing burns in humans and animals, for example, complex Zn( ii ) sulfadiazine. Their effectiveness does not depend solely on slow release ion, but rather strongly nature material which bound. Given ability derivatives coordinate with atoms ways, considerable interest synthesis structural aspects new has arisen. These results confirm significant chemical capacity sulfonamides act as based acidity its gives donor anionic ligand, allied presence vicinal nitrogen, sulfur or oxygen heterocyclic ring, provide stereochemical requirements realization monodentate chelating agent bridging providing monomeric structures, dimeric arrangements polymers. aromatic amino group responsible versatility sulfonamides, since it coordination site, reactive site modifications very interesting biological purposes. present work, structure novel sulfanilamide complex: nitro (4-aminobenzenesulfonamide) zirconium was presented. Characterization performed by infrared spectroscopic, thermogravimetric X-ray diffraction analysis.